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Leiden University

Medical Center

Leiden University Medical Center stands as a world-class academic hospital that bridges science and patient care. Rooted in centuries of academic excellence and guided by a global outlook, LUMC continues to shape the future of medicine while upholding the values of curiosity, integrity, and humanity.
A distinctive strength of LUMC is its leadership in image-guided therapy, an innovative field that combines advanced imaging technologies with minimally invasive therapeutic procedures. Through the Leiden Image-Guided Therapy (LIGT) Center, LUMC brings together clinicians and researchers to develop precision-based interventions guided by real-time imaging. The LIGT Center integrates advanced medical imaging, robotics, data science, and interventional techniques to improve accuracy, reduce patient risk, and accelerate recovery. This approach exemplifies LUMC’s commitment to translating technological innovation into safer and more effective patient care.

Contribution to PreciseOnco

Leiden University Medical Center is the leading institute for the clinical studies SPOT ON and HORA EST HCC II.

Team

Prof. Dr. Mark C. Burgmans

Prof. Dr. Mark C. Burgmans is an interventional radiologist and clinical researcher at Leiden University Medical Center (LUMC), where he serves as Head of Interventional Radiology and leads the Interventional Radiology Research Group (IR²).
 
His work focuses on advancing image‑guided, minimally invasive therapies in interventional oncology and vascular care. He is internationally recognized for developing and implementing advanced imaging platforms, including hybrid Angio‑CT systems for precise cancer treatments. Dr. Burgmans played a key role in establishing the Leiden Image‑Guided Therapy Center, integrating advanced imaging, robotics, and data‑driven technologies. A former Chair of the Dutch Society of Interventional Radiology, he is active in CIRSE and serves as Deputy Editor‑in‑Chief of CVIR Oncology. His research spans thermal ablation, spectral CT, AI, robotics, and sustainability.

Jouke Dijkstra, PhD

Jouke Dijkstra, PhD, is an Associate Professor of Medical Imaging and AI at the Radiology Department of Leiden University Medical Center.
 
He has worked in the Image Processing Division since 1996 and leads research in vascular imaging, with a focus on intravascular ultrasound, optical coherence tomography, and CT angiography. He also oversees imaging post‑processing research, including image‑guided surgery and interventional imaging. His group has developed deep‑learning methods for organ and tumour segmentation and classification, notably for liver and pancreas applications, with strong emphasis on clinical validation and implementation. Jouke has coordinated multiple large research projects, including long‑running ITEA initiatives. In the IHI PreciseOnco project, he investigates the value of spectral Angio‑CT for structure segmentation and solution evaluation.

Alexander Broersen, PhD

For more than 15 years, Alexander Broersen has been working as a researcher in the group for medical image processing as part of the department of Radiology of the Leiden University Medical Center.

During his PhD, he worked at the national research institute for mathematics and computer science on automatic feature extraction and visualization of large scale imaging mass spectrometry data. His current research is on the co-registration, image fusion, 3D modeling and automatic quantification of medical images using both classical and deep learning approaches. Although he started in the field of cardiovascular imaging on computed tomography angiographic scans, he is currently also active in other fields such as liver and pancreas oncology, aortic aneurisms and dissections.

Emma Buijsman, MSc

Emma Buijsman is a PhD candidate in the Radiology Department at Leiden University Medical Center, where she is part of the PreciseOnco project. She holds a BSc in Clinical Technology and an MSc in Technical Medicine, both obtained through a joint degree between Delft University of Technology, Leiden University, and Erasmus University Rotterdam. This training forms the foundation of the Technical Physician profession, a Dutch discipline that bridges the clinical and technical aspects of healthcare. Her master’s research focused on the development of a prognostic model for hepatocellular carcinoma following thermal liver ablation, combining imaging and clinical parameters to predict early recurrence.

She now continues performing research in interventional oncology, contributing to the PreciseOnco project with a focus on advancing image-guided cancer treatment through spectral Angio-CT.